Scientific Publications

Scientific Publications

 

Sax, C.M., Kays, W.T., Salamon, C., Chervenak, M.M., Xu, Y.S., Piatigorsky, J. (2000) Transketolase Gene Expression in the Cornea is Influenced by Environmental Factors and Developmentally Controlled Events. Cornea 19:833-841.

 

Jester, J.V., Moller-Pederson, T., Huang, J., Sax, C.M., Kays, W.T., Cavangh, H.D., Petroll, W.M., Piatigorsky, (1999) J. Cell Sci. 112:613- 622.

 

Regulation of aA-crystallin gene expression: lens-specificity achieved through the differential placement of similar transcriptional control elements in mouse and chicken. J. Biol. Chem. 274:19973-1978. 

 

Salamon, C., Chervenak, M., Piatigorsky, J., Sax, C.M. (1998) The mouse transketolase (TKT) gene: cloning, characterization, and functional promoter analysis. Genomics 48:209-220.

 

Sax, C.M., Cvekl, A., Piatigorsky, J. (1997) Transcriptional regulation of the mouse aA-crystallin gene: binding of USF to the -7/+5 region. Gene 185:209-216.

 

Guo, J., Sax, C.M., Piatigorsky, J., Yu, F.X. (1997) Heterogeneous expression of transketolase in ocular tissues. Cur. Eye Res. 16:467-474.

 

Sax, C.M., Ilagan, J.G., Haynes, J.I. (1996) Lens-preferred activity of the -1809/+46 mouse aA-crystallin promoter in stably integrated chromatin. Biochim. et Biophys. Acta 1305:49-53.

 

Sax, C.M., Salamon, C., Kays, W.T., Yu, F.X., Cuthbertson, R.A., Piatigorsky, J. (1996) Transketolase is a major protein in the mouse cornea. (1996) J. Biol. Chem. 271:33568-33574.

 

Krausz, E., Augusteyn, R.C., Quinlan, R.A., Reddan, J.R., Russell, P., Sax, C.M., Graw, J. (1996) Expression of crystallins, Pax6, Filensin, CP49, MIP and MP20 in lens-derived cell lines. Invest. Ophthal. Vis. Sci. 37:2120- 2128.

 

Sax, C.M., Cvekl, A., Kantorow, M., Gopal-Srivastava, R., Ilagan, J., Ambulos, N.P., Jr., Piatigorsky, J. (1995) Lens-specific activity of the mouse aA-crystallin promoter in the absence of a TATA box: functional and protein binding analysis of the mouse aA-crystallin PE1 region. Nucl. Acids Res. 23:442-451.

 

Sax, C.M., Dziedzic, D.C., Piatigorsky, J., Reddan, J.R. (1995) Analysis of a-crystallin expression in cultured mouse and rabbit lens cells. Exp. Eye Res. 61:125-127, 1995.

 

Brady, J.P., Kantorow, M., Sax, C.M., Donovan, D.M., Piatigorsky, J. (1995) A molecular analysis of the gene encoding the mouse transcription factor aA-CRYBP1. J. Biol. Chem. 270:1221-1229.

 

Cvekl, A., Kashanchi, F., Sax, C.M., Brady, J.N., Piatigorsky, J. (1995) Transcriptional regulation of the mouse

aA-crystallin gene: activation dependent on a cyclic AMP resposive element (DE1/CRE) and Pax-6 binding site. Mol. Cell. Biol. 15:653-660.

Cvekl, A., Sax, C.M., Li, X., McDermott, J.B., Piatigorsky, J. (1995) Pax-6 and lens-specific transcription of the chicken d1-crystallin gene. Proc. Natl. Acad. Sci. 92:4681-4685.

 

Chambers, C., Cvekl, A., Sax, C.M., Russell, P. (1995) Sequence, initial functional analysis and protein-DNA binding sites of the mouse bB2-crystallin-encoding gene. Gene 166:287-292.

 

Sax, C.M., Cvekl, A., Kantorow, M., Sommer, B., Chepelinsky, A.B., Piatigorsky, J. (1994) Identification of negative-acting and protein-binding regions within -1559/-1165 of the mouse aA-crystallin promoter. Gene 144:163-169.

 

Sax, C.M., Piatigorsky, J. (1994) Expression of the a-crystallin/small heat shock protein/molecular chaperone genes in the lens and other tissues. Advan. Enzymol. 69: 155-201.

 

Cvekl, A., Sax, C.M., Bresnik, E.H., Piatigorsky, J. (1994) A complex array of positive and negative elements regulates the chicken aA-crystallin gene: involvement of Pax-6, USF, CREB and/or CREM, and AP-1 proteins. Mol. Cell. Biol. 14:7363-7376.

 

Sax, C.M., Ilagan, J.G., Piatigorsky, J. (1993) Functional redundancy of the DE-1 and aA-CRYBP1 regulatory sites of the mouse aA-crystallin promoter. Nucl. Acids Res. 21:2633-2640.

 

Sax, C.M., Stover, D.M., Ilagan, J.G., Zehner, Z.E., Piatigorsky, J. (1993) Functional analysis of chicken vimentin distal promoter regions in cultured lens cells. Gene 130:277-281.

 

Kantorow, M., Cvekl, A., Sax, C.M., Piatigorsky, J. (1993) Protein-DNA interactions of the mouse aA- crystallin control regions: differences between expressing and non-expressing cells. J. Mol. Biol. 230:425- 435.

 

Kantorow, M., Becker, K., Sax, C.M., Ozato, K., Piatigorsky, J. (1993) Binding of tissue-specific forms of aA- CRYBP1 to its regulatory sequence in the mouse aA-crystallin gene: Double-label immunoblotting of UV- crosslinked complexes. Gene 131:159-165.

 

Sax, C.M., Klement, J.F., Piatigorsky, J. (1992) Role of the aA-CRYBP1 site in lens-specific expression of the aA-crystallin gene. in Biotechnology and Environmental Science: Molecular Approaches, Mongkolsuk, S., Lovett, P.S., Trempy, J. (eds.), Plenum Publishing Corp., NY, NY, pp. 27-33.

 

Donovan, D.M., Sax, C.M., Klement, J.F., Li, X., Chepelinsky, A.B., Piatigorsky, J. (1992) Conservation of mouse aA-crystallin promoter activity in chicken lens epithelial cells. J. Mol. Evol. 35:337-345.

Sax, C.M., Farrell, F.X., Zehner, Z.E., Piatigorsky, J. (1990) Regulation of vimentin gene expression in the ocular lens. Develop. Biol. 139:56-64.

 

Sax, C.M., Klement, J.F., Piatigorsky, J. (1990) Species-specific lens activation of the thymidine kinase promoter by a single copy of the mouse aA-CRYBP1 site and loss of tissue-specificity by multimerization. Mol. Cell. Biol. 10:6813-6816.

 

Farrell, F.X., Sax, C.M., Zehner, Z.E. (1990) A negative element involved in vimentin gene expression. Mol. Cell. Biol. 10:2349-2358.

 

Nakamura, T.S., Donovan, D.M., Hamada, K., Sax, C.M., Norman, B., Flanagan, J.R., Ozato, K., Westphal, H., Piatigorsky, J. (1990) Regulation of the mouse aA-crystallin gene: isolation of a cDNA encoding a protein that binds to a cis sequence motif shared with MHC class I and other genes. Mol. Cell. Biol. 10:3700-3708.

 

Flannery, D.B., Sax, C.M., Thurmon, T.F. (1990) Craniofrontonasal dysplasia. in Birth Defects Encyclopedia, Buyse, M.L. (ed.), Birth Defects Information Services, Dover, MA, pp. 459-460.

 

Sax, C.M., Farrell, F.X., Zehner, Z.E. (1989) Down-regulation of vimentin gene expression during myogenesis is controlled by a 5′-flanking sequence. Gene 78:235-242.

 

Farrell, F.X., Sax, C.M., Garzon, R.J., Zehner, Z.E. (1989) Regulation of vimentin expression during myogenesis. In Cellular and Molecular Biology of Muscle Development, L.H. Kedes & F.E. Stockdale (eds), Alan R. Liss Inc., NY, NY. Vol. 93, pp. 777-788.

 

Sax, C.M., Farrell, F.X., Tobian, J.A., Zehner, Z.E. (1988) Multiple elements are required for expression of an intermediate filament gene. Nucl. Acids Res. 16:8057-8076.

 

Zehner, Z.E., Li, Y., Roe, B.A., Paterson, B.M., Sax, C.M. (1987) The chicken vimentin gene: nucleotide sequence, regulatory elements, and comparison with the hamster gene. J. Biol. Chem. 262:8112-8120.

 

Sax, C.M., Flannery, D.B. (1986) Craniofrontonasal dysplasia: clinical and genetic analysis. Clin. Gen. 29:508-515.

 

Sax, C.M., Bodurtha, J.N., Brown, J.A. (1986) Case report: partial trisomy 20q (20q13.13-qter). Clin. Gen. 30:462-465.

 

Wilhelm, J.M., Spear, P., Sax, C. (1982) Heat-shock proteins in the protozoan Tetrahymena: induction by protein synthesis inhibition and possible role in carbohydrate metabolism. in Heat Shock. From Bacteria to Man, Schlesinger, M.J., Ashburner, M., Tissieres, A. (eds.), Cold Spring Harbor Laboratories, NY, pp. 309- 314.